The Conti Method: Building Lasting Psychological Well-being Through 4 Pillars
Anxiety, depression, burnout, addictions… Our mental health has never been tested so much. Faced with this observation, Dr. Paul Conti, eminent psychiatrist and professor at Stanford, an innovative approach to help us regain control of our minds. His secret? Four basic pillars – mind structure, self function, empowerment and gratitude – to build the foundation of lasting psychological well-being. Decryption method is as simple as it is powerful.
The structure of the mind: diving into the depths of our psyche
The first pillar of the Conti method: understanding the personal architecture of our minds. Far from clichés about the brain, it is about exploring the different layers that shape our psychological life:
- The unconscious mind, a real “computer” that keeps track of our thoughts and behavior without us knowing
- The conscious mind, the tip of the iceberg, the seat of our “self” and our apparent free will
- Defense mechanisms, these unconscious “tentacles” that protect ourselves from external attacks
- Character structure, this “shell” created by our experience determines how we interact with the world
Far from being a simple reading grid, this mental model is a powerful tool for introspection.
Diabetic retinopathy: a silent epidemic
Diabetic retinopathy, an ocular complication of diabetes, is positioned as a global public health concern.
It is estimated that approximately 93 million people in the world live with diabetic retinopathy, and this number is expected to increase to 160 million by 2040 if adequate preventive and treatment measures are not taken.
Who it affects and how it develops
Diabetic retinopathy is an eye condition that affects people who have diabetes, especially those with poor glycemic control over time. It is estimated that at least one third of people with diabetes will develop some degree of diabetic retinopathy during their lifetime.
It is crucial to highlight that diabetic retinopathy can be asymptomatic in its initial stages, which underlines the importance of performing regular ophthalmological examinations, at least every six months, to detect any early signs of the disease. As the condition progresses, symptoms may arise such as blurred vision in the central part, a result of elevated blood glucose levels, as well as the presence of macular edema, characterized by bleeding and the accumulation of fatty deposits in the retina.
Treatments and hope
The treatment of diabetic retinopathy depends on the state of the disease.
Smart imaging to improve cell therapy
#Smart #imaging #improve #cell #therapy
Scientists can visualize live how CAR T-cell therapy and other immunotherapies work in hematological tumors. This is possible thanks to an extension of an advanced imaging tool previously developed for solid tumors. Researchers from the Princess Máxima Center published about it in Nature Protocols.
To better understand who can benefit from cell therapies, it is essential to learn more about how the engineered immune cells and tumor cells interact. The Rios group of the Princess Máxima Center developed a 3D imaging technique that provides live insight into the interaction between immune and tumor cells.
The imaging tool, called BEHAV3D, can detect immune cells that show behavior that makes them more effective at destroying tumor cells. This allows the most promising immune cells to be found for therapeutic use. The imaging tool has even more applications. The researchers can use it to study behavioral differences in many different immune cells and forms of cancer.
For example, they saw remarkable differences in the way T cells respond to tumor cells in liquid or solid tumors. In blood cancers they move from one cell to another and behave like ‘serial killers’.
A new genetic form of Alzheimers disease identified. Medicine in the Library
A new genetic form of Alzheimer’s disease identified.
Posted by giorgiobertin on May 7, 2024
The results of this study conducted by researchers at Research Area on Neurological Diseases, Neuroscience, and Mental Health at the Sant Pau Research InstituteSpain, indicate that the APOE4 form of the APOE gene, already “investigated” for some time in the context of Alzheimer’s, is strongly correlated with the risk of onset of the disease.
In particular, people whose genome contains a double copy of this form of the gene – called APOE4 homozygotes – have a very high probability of developing the disease and of developing it earlier than those with other variants of the same gene. So much so that homozygosity for APOE4 could represent a new genetic form of the disease.
In this work, researchers evaluated clinical, pathological, and biomarker changes in APOE4 homozygotes to determine their risk of developing Alzheimer’s disease.
The findings suggest that virtually all APOE4 homozygotes exhibited Alzheimer’s pathology and had higher levels of disease-associated biomarkers at age 55 compared to individuals with the APOE3 gene.
The authors highlight that these findings could be useful for the development of personalized prevention strategies,
Worlds First Documented Case of Brain Disease from Inhaling Fentanyl Reported in Oregon
Doctor analyzing patients brain scan on screen (Getty Images)
The Silent Epidemic: The Rise of Fentanyl-Related Brain Disease
A shocking case of brain disease caused by inhaling fentanyl has alarmed medical professionals and raised concerns about the growing dangers of illicit drug use. In a groundbreaking study published in the BMJ Case Reports, Oregon Health & Science University (OHSU) revealed that a previously healthy 47-year-old man had become the world’s first documented case of toxic leukoencephalopathy resulting from fentanyl inhalation.
The patient, who arrived at an Oregon emergency room unconscious and near death, was found collapsed in his hotel room during a business trip. Initial tests for opioids showed negative results, leading doctors to embark on an exhaustive search for the underlying cause.
According to the hospital, inhaling fentanyl led to large sections of white matter in the patient’s brain becoming inflamed to the point he lost consciousness and was at risk of irreversible loss of brain function or death.
This unprecedented diagnosis serves as a wake-up call: while previous cases have demonstrated similar diagnoses with patients inhaling heroin, this particular instance marks the first known occurrence involving illicit fentanyl inhalation. Driven by its potent effects and easy availability,
The Ultimate Guide to Understanding Aurora Formation and Types
The process of aurora formation begins with the interaction of charged particles. These particles, such as protons and electrons, come from sun (solar wind) with atoms in the Earth’s atmosphere. So it happened then a heavenly phenomenon This.
Read also: Information about Aurora Borealis, A Beautiful Light that Makes a Sound?
These charged particles are repelled by a magnetic field Earth, so it is located in the polar regions. When these particles interact with atoms in the atmosphere, their energy is released in the form of light, producing the beautiful glow known as auroras.
Investigating the types and process of the Aurora event
In the polar air Earthnature provides an amazing light show, moving an indescribable beauty.
In the southern hemisphere, this phenomenon is called the southern lights or aurora australis. At the same time at the north pole, this light dance is the aurora polaris, borealis, or northern lights.
Both southern lights and northern lights have the same process of creation, which is the interaction of charged particles sun (solar wind) with atoms in the Earth’s atmosphere.
These particles are bound by a magnetic field Earth and based in the polar regions.
The evolutionarily newest part of the human brain is more peculiar than believed
The neocortex, a structure essential for human intelligence, is less than five millimeters thick. There, in the outermost layer of the brain, 20 billion neurons process countless sensory perceptions, plan actions, and form the basis of our consciousness. How do these neurons process all this complex information? That largely depends on how they are connected to each other.
What was known until now about the neuronal architecture of the human neocortex was based mainly on findings made from studying animal models such as mice.
The human neocortex is much thicker and more complex than that of the mouse. However, the scientific community had until now assumed (partly due to lack of data) that it followed the same basic principles of connectivity.
Now, in a new study, for which cutting-edge technology and exceptionally difficult to obtain tissue samples have been used, it has been proven that, contrary to what was assumed until now, the nerve cells of the human neocortex are very connected. different from those of mice.
The study was carried out by a team including, among others, Yangfan Peng and Jörg Geiger, from the Neuroscience Research Center, attached to the Charité University Hospital in Berlin,
The Impact of Temperature Fluctuations on Skin Diseases: Understanding and Treating Tinnitus
[미디어파인 전문칼럼] As the temperature difference between day and night increases, the immune system weakens and skin diseases such as rashes, atopy and psoriasis can worsen, so it is necessary to be in the company of others.
Tinnitus is a superficial skin infection caused by Malassezia, a type of fungus.
It occurs mainly on the upper part of the body, particularly on the chest, back, armpits and neck, where sebum secretion is high. Mold can be commonly observed in our daily lives. It is especially common during the hot and humid summer season and tinnitus also occurs frequently during these seasons and recurs repeatedly.
The most characteristic feature of tinea rash is the mottled spots like ringworm. Colors vary widely, from flesh-colored to white, pink or brown. Because tinnitus manifests itself in clusters of small, round spots around the pores, nearby spots clump together and merge together to form slightly larger spots. And it has the characteristic of dead white skin cells growing over the spots.
Because this condition has no obvious symptoms, it cannot be actively treated in the early stages and often easily becomes chronic. When it becomes chronic, it continues to recur and the skin depigmentation reaction becomes more severe due to the toxins produced by the fungus.
Diet that you should follow if you are a former smoker
If you are looking to take care of your health through food, it is the best thing you can do. Medical specialists affirm that it is the foods we decide to consume that keep our body’s immune system strengthened, as well as physical activity and regular check-ups.
On more than one occasion we have highlighted the nutrients and properties that many foods from nature have for our health. And it is in this regard that today we want to tell you about the diet that those people with a history of smoking should follow to avoid suffering from emphysema.
The Mayo Clinic Institute notes that emphysema is a lung condition that causes difficulty breathing. Those who suffer from emphysema have damaged air sacs in their lungs, meaning that they have weakened over time and end up breaking. Its specialists affirm that smoking is the main cause of this disease, so it is necessary to do something to prevent it.
In this framework, a study reveals that those who smoke or have had a history related to smoking can reduce the chances of suffering from emphysema. To do this, they would have to implement a diet based on fruits and vegetables,