London (IT Boltwise) – A current study has once again emphasized the connection between severe viral infections and neurodegenerative diseases such as Alzheimer’s and Parkinson’s. The analysis of 500,000 medical data records shows that certain viral infections can significantly increase the risk of these diseases.
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A comprehensive study published in 2023 has once again emphasized the connection between severe virus infections and neurodegenerative diseases such as Alzheimer’s and Parkinson’s. The researchers analyzed around 500,000 medical data records and found 22 significant connections between viral infections and neurodegenerative diseases. It was particularly striking that people who were treated for viral encephalitis had a 31-way risk of developing Alzheimer’s.
The study also showed that patients who suffered from pneumonia after flu were more susceptible to Alzheimer’s, dementia, Parkinson’s and amyotrophic lateral sclerosis. Daring infections and meningitis, which are often caused by viruses, as well as the Varicella Zoster virus, triggers belt rose, were also associated with the development of several neurodegenerative diseases.
A remarkable aspect of the study is that the effects of viral infections on the brain can last up to 15 years in some cases. The researchers emphasized that there were no cases in which exposure to viruses had a protective effect. Around 80 percent of the viruses associated with brain diseases are considered ‘neurotropic’, which means that they can overcome the blood-brain barrier.
The researchers pointed out that vaccines are already available for some of these viruses, including for influenza, belt rose (varicella zoster) and pneumonia. Although vaccines do not prevent all illnesses, they are known to significantly reduce the hospitalization rates. This indicates that vaccinations could possibly reduce the risk of developing neurodegenerative diseases.
In an earlier study from 2022, the Epstein-Barr virus was associated with a 32-fold increased risk of multiple sclerosis. The researchers led this findings to a new, data science approach in which they systematically searched for all possible connections between viral infections and neurodegenerative diseases.
The results of this retrospective observation study cannot demonstrate any causal relationships, but they add the growing number of research results to indicate the role of viruses in the development of Parkinson’s and Alzheimer’s. The researchers emphasize that viral infections and the associated inflammation of the nervous system may represent avoidable risk factors for these diseases.
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