One step closer to controlling the healing process: Its like being able to turn on a tap and regulate the collagen you need
2024-04-24 09:00:00
Updated Wednesday, April 24, 2024 – 11:00
When an injury occurs, the active organism the process of scaracin to close that injury. Basically, the mechanism consists of the secretion and accumulation of different substances, among which collagen stands out, in the space between the cells. sometimes a Excessive collagen secretion can cause the accumulation of fibrotic tissuewhich can lead to complications, especially if it is generated in an internal organ after, for example, surgery.
Being able to avoid this excess is a little closer thanks to the work of a team from the Center for Genomic Regulation of Barcelona and the University of Cologne (Germany) who has developed an experimental approach aimed at controlling the effects of collagen hypersecretion.
This strategy is based on using small molecules capable of interrupting the interaction between the TANGO1 and cTAGE5 proteins, a key ‘bridge’ in collagen export at the cellular level.
At the moment they have tried the novel strategy in human cells derived from patients and in animal models and have proven that it is effective, reversible and does not produce toxicity. All details have been published in the latest issue of Nature Communications.
2024 Paris Olympics Badminton Qualifications: Hong Kong Teams Success Story
2024-04-17 12:02:39
[Tilu News]The World Badminton Federation updated the Paris Olympic rankings on Wednesday (17th). There will be no more World Tour stops before the end of the scoring cycle at the end of the month. The qualifications can be said to have been settled. The Hong Kong team has won 4 Among the admission tickets, the mixed doubles “Deng Xie Pair” Tang Chunwen/Tse Yingsuet are once again shortlisted after the Tokyo Olympics; the men’s singles Li Zhuoyu, the women’s singles Lu Shanyan and the women’s doubles Yang Peilin/Yang Yating will compete in the Olympics for the first time respectively.
Qualifications for the 2024 Paris Olympics are determined by Olympic rankings. Although the scoring cycle only ends on April 30, after the completion of the Asian Championships and other continental championships over the past weekend, there are no World Tour-level events for athletes to compete for points. Only those with very few points. Therefore, after the updated Olympic rankings are released as of Tuesday, it can basically be regarded as the implementation of Olympic qualifications. Each badminton singles event at the Paris Olympics has 35 seats. If more than one athlete from each country or region ranks in the top 16,
UMA researchers lead a study on the role of the PCSK9 protein in liver disease
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MÁLAGA, 24 Abr. (EUROPA PRESS) –
A team of researchers from the University of Malaga (UMA) and the Virgen de la Arrixaca Hospital in Murcia have recently published a study in which they analyze the blood and liver levels of PCSK9, a protein that regulates the transport of cholesterol to the liver in people. with liver disease, a pathology that affects this organ, preventing it from working correctly.
To do this, as reported by the UMA in a statement, they have had liver samples provided by 110 obese patients who underwent bariatric surgery, a technique used to induce weight loss in people with extreme obesity.
The levels of this PCSK9 protein were measured before and after (six months) bariatric surgery in blood samples. In addition, the levels of PCSK9 protein and PCSK9 messenger RNA – the molecule from which the protein is created – were measured in the liver by immunohistochemistry and RT-qPCR.
They have pointed out that to better understand these concepts, the researcher of the Department of Surgical Specialties, Biochemistry and Immunology, Fernando Cardona Díaz, one of the promoters of the study,
Breaking the Taboo: Men and Aesthetic Medicine Demystifying Prejudices and Stigmas
Men breaking barriers in aesthetic medicine: 1 in 4 have undergone treatment
Men who use aesthetic medicine are facing social stigma and prejudices, but they are slowly breaking barriers and debunking the myth that this practice is only for women. According to a study by Teoxane, a company specializing in hyaluronic acid, in collaboration with Nielsen, 1 in 4 men has undergone an aesthetic medicine treatment and up to 60% would be interested in doing so in the future.
Dr. Raúl Navarro explains that men are increasingly focused on preventing aging and promoting healthy aging. He notes, “Aesthetic medicine has evolved to where men are more proactive in their approach to lifestyle, beauty, and health.” The study reveals that men under 41 years of age are the most likely to seek out aesthetic treatments.
While some men may initially dismiss the idea of aesthetic medicine, many are open to changing their minds if they see positive results in others. Dr. Navarro emphasizes that seeing successful outcomes in other men can help alleviate any concerns or skepticism about undergoing aesthetic treatments.
Despite the growing acceptance of male aesthetic medicine, there are still some who hold prejudices.
First Ever Transplant Surgery Combines Mechanical Heart Pump and Gene-Edited Pig Kidney
The Future of Organ Transplants: Combining Technology and Innovation
The field of organ transplantation has reached new frontiers with the groundbreaking surgery recently performed at NYU Langone Health. A 54-year-old woman named Lisa Pisano, who suffered from heart failure and end-stage kidney disease, became the first recipient to undergo a transplant that combined a mechanical heart pump with a gene-edited pig kidney.
Traditional transplant options were not feasible for Pisano due to her underlying chronic conditions and the scarcity of donor organs in the United States. However, this innovative procedure offered hope for a positive outcome in her case.
In recent years, there has been an increasing demand for organs far surpassing their availability. Shockingly, each day in America, an average of 17 individuals lose their lives while awaiting appropriate organ donations. Among all organs needed, kidneys are particularly scarce. As per data from the Organ Procurement and Transplantation Network, only around 27,000 kidneys were transplanted in 2023 while almost 89,000 individuals remained on the waiting list.
To address this pressing issue and bridge the gap between supply and demand for organs, experts have turned to xenotransplants – the transplantation of animal organs into humans.
The Importance of Vitamins for Athletes: Essential Nutrients for Energy and Performance
Vitamins are always important, but which ones are necessary for them a tired fightespecially for them practice sports? We talked about it with Christian Faffini, nutritionist and dietitian at MioDottore. “The essentials, especially for athletes, include B complex vitamins (B12, B6, folic acid), C, D, E. They perform a fundamental role in energy metabolismin cellular energy production, in bone and muscle health and in the elimination of toxins after intense physical activity. It is important to ensure that they take in from a balanced diet and, if necessary, supplement them with food supplements, under the guidance of a healthcare professional.” These affect your energy level during intense physical activity in a number of ways. “The vitamins of B complex – continues with the expert – they are necessary for the carbohydrate metabolismproteins and fats, providing energy to the body during exercise, important for the nervous system, improving the transmission of nerve impulses to the muscles: C and E, along with materials such as Selenium is manganesethey work like antioxidants, neutralization of free radicals produced during physical activity, reduce muscle fatigue. The vitamin It’s K support bone and muscle health. In summary, vitamins play a fundamental role in providing energy, protecting cells,
The use of AI for mental health will generate 2.5 billion euros in Spain by 2030
The artificial intelligence (AI) It is coming to stay and revolutionize all types of areas, such as health. Within this sector, new ones are emerging in Spain star-ups whose objective is to create technological solutions that take advantage of AI to introduce improvements in mental healthboth for patients and professionals.
Among the latest milestones related to mental health and AI is MoodCapture, an application that can help detect mental health illnesses by analyzing several facial photographs of the patient. The creators, a group of scientists from the Dartmouth Universitythey assure that this tool can notice mental illnesses even before the person themselves realizes that they may be suffering from one.
With more and more proposals on the table and innovation in this regard, great growth in the sector’s business volume is expected. Yes in 2023 the use of the AI in the field of mental health generated around 920 million of dollars, a study of Polaris Market Research anticipates that by 2032 almost 10,335 will move millions.
AI and mental health in Spain
In Spain, multiple start-ups with the aim of providing solutions for mental health through artificial intelligence.
Unlocking the Secrets of Birthmarks: What Your Red and Black Birthmarks Say About You
Many people have probably heard that Anyone who has a black birthmark or a red birthmark means he or she is reborn. And not an ordinary person. There must be something special. But do you know the location of the birthmark? It can tell stories. Man Garin opens ancient texts. Predict the location of black and red birthmarks on the body. Which area can tell the owner’s personality? How will it be?
Birthmarks around the eyes
People who have red or black birthmarks around their eyes I am a sociable, fun-loving and easy to get along with person. But they often have problems with love or unlucky love.
Birthmarks on the face
People who have red or black birthmarks on their face Even if it’s an area that no one wants there. Because it is an obvious and captivating point. But people who have cravings in this area are usually hardworking people, good at earning money and diligent in their work.
Birthmarks on the neck
People with birthmarks in this area tend to be introverted. I don’t like to socialize Or called an introvert, but also a person with good intelligence, good memory and ability.
Vitamin you should consume if you want to get pregnant
Did you know that a pregnant woman needs a daily intake of approximately 800 micrograms of vitamin A, according to the Recommended Dietary Allowances? Although this value is equivalent to a medium carrot, what many people looking to get pregnant do not take into account is that this vitamin also promotes fertility.
What are the benefits of Vitamin A?
It is an essential nutrient for the human body, with a variety of important functions that go beyond simply maintaining good vision.
This compound, also known as retinol or retinoic acid, plays a crucial role in vision, growth, cell division, reproduction and immunity. It also has antioxidant properties that protect cells against free radicals, molecules that can contribute to the development of heart disease, cancer and other pathologies.
There are two main forms of vitamin A in the human diet: preformed vitamin A, present in products of animal origin such as meat, fish and dairy products, and provitamin A carotenoids, present in intensely colored fruits and vegetables, such as carrots, broccoli and spinach. Carotenoids, such as beta-carotene, are converted to vitamin A in the body and are an excellent source of this nutrient.