The growing global interest in a longer, healthier life has fueled extensive research on nutrition and aging. A recent report supported by the Spanish Society of Anti-Aging and Longevity Medicine identified five nutrients with the greatest scientific support for their ability to prevent chronic diseases and improve quality of life. Although most of the data comes from animal studies, the first human trials offer encouraging results on how proper nutrition can influence aging processes.
The first is resveratrol, a polyphenol present in grapes and red fruits, known for its antioxidant, anti-inflammatory and immunomodulatory properties. Although it improves parameters such as cholesterol, glucose and endothelial function, there is still no conclusive evidence that it prolongs human life. Its action is linked to the activation of sirtuins, but clinical trials show variable results and there is no consensus on the ideal dose.
Quercetin, a flavonoid found in onion, apple and citrus fruits, acts as an antioxidant and anti-inflammatory, and also has a senolytic effect, that is, it helps eliminate aging cells. In human studies, reductions in blood pressure, cholesterol and senescent cells were observed, especially in people with diabetes, and their impact on diseases associated with aging is being investigated.
Vitamin B3 and its derivatives, such as riboside and nicotinamide mononucleotide, play a central role in the production of NAD+, key for energy metabolism and DNA repair. In humans, its supplementation showed improvements in blood pressure, energy and body composition without relevant adverse effects.
Vitamin D is essential for bone, muscle and immune health, and its deficiency is common in older adults. Finally, glycine, an amino acid present in meat and fish, showed benefits on longevity, cardiovascular function and cellular energy in animal models, especially combined with N-acetyl-cysteine. Experts emphasize that these nutrients must be integrated into a balanced diet and adapted to each person.
With information from Infobae
