Sickle Cell & Pregnancy: WHO Guidelines

by Archynetys Health Desk

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<a href="https://www.nhlbi.nih.gov/health/sickle-cell-disease" title="Sickle Cell Disease - What Is Sickle Cell Disease? | NHLBI, NIH" target="_blank" rel="noopener">Sickle Cell Disease</a> and Pregnancy: New Guidelines for Healthcare Providers


Sickle Cell Disease and Pregnancy: New Guidelines for Healthcare Providers

Guidelines aim to improve care for pregnant women with sickle cell disease, addressing important health risks.


By Alice Smith | LONDON – 2025/06/19 05:28:48

Sickle-cell disease (SCD), a group of autosomal recessive haemoglobin disorders resulting from a gene mutation in the β-subunit of haemoglobin, affects 7.74 million people worldwide. the condition is notably prevalent in sub-Saharan Africa,but also poses a significant disease burden in other historically malaria-endemic regions,including the Middle East,the Caribbean,and South asia. Women with SCD face a higher risk of pregnancy complications.

New guidelines have been released to aid healthcare providers in managing pregnancies affected by SCD. These guidelines are designed for obstetricians,midwives,nurses,and general practitioners directly involved in providing care to women during pregnancy and childbirth. They are also intended for healthcare providers responsible for developing national and local healthcare protocols and policies,as well as managers of maternal and child health programs,and policymakers.

Improving Clinical Care and Training

“Women who live with SCD are at higher risk for pregnancy complications.”

The guidelines provide data useful for developing clinical tools for pre- and in-service training of health workers and health-system strengthening efforts, ultimately enhancing the delivery of clinical care.

Resources and Further Information

Additional resources include evidence-to-decision frameworks and related links to maternal health initiatives.

Frequently Asked Questions about Sickle Cell Disease and Pregnancy

What are the risks of sickle cell disease during pregnancy?

Women with SCD face increased risks of complications such as pre-eclampsia, preterm birth, and vaso-occlusive crises [[19]], [[20]].

How can healthcare providers manage sickle cell disease during pregnancy?

Management includes regular monitoring, pain management, blood transfusions, and prompt treatment of complications [[21]], [[22]].

Where can I find more information about sickle cell disease?

Reliable sources include the Centers for Disease Control and Prevention (CDC) and the National Heart, Lung, and Blood Institute (NHLBI) [[23]],[[24]].

About the Author

Alice Smith is a health reporter specializing in maternal health and genetic disorders. She is committed to providing accurate and accessible information to the public.


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