New way to enhance the effect of drugs that reduce cholesterol
2024-02-07 10:45:27
Scientists have identified an important mechanism through which atherosclerosis plaque regression can be achieved. The study reveals cells derived from smooth muscle as a new target on which to direct future therapies.
The research is the work of a team from the National Center for Cardiovascular Research (CNIC), a center dependent on the Carlos III Health Institute (ISCIII), an organization attached to the Ministry of Science, Innovation and Universities of Spain, and the University of Aarhus, in Denmark,
The identified mechanism is based on a type of inflammatory signaling in the cellular subsets of smooth muscle cells involved in the growth of atherosclerosis plaques. According to Jacob F. Bentzon, head of the participating teams at the CNIC and Aarhus University, “its discovery opens up new opportunities to design therapies aimed at enhancing the beneficial effect of cholesterol-lowering drugs and leading to a more effective regression of lesions in patients with advanced atherosclerosis.
Smooth muscle cells make up the wall of arteries and proliferate and transform into alternative cell types during atherosclerosis, responsible for cardiovascular and cerebrovascular disease, such as heart attacks or strokes.
Blood cholesterol is the main cause of atherosclerosis,
Understanding Skin Sensitivity: Symptoms, Causes, and Improvement Methods
2024-02-06 09:46:28
Read more about skin sensitivity symptoms, causes and improvement methods in this article
related articles:
There are many causes of skin sensitivity. In addition to genetic factors, it may also be caused by personal emotions, physical contact with certain skin care products, cleaning products, or external environmental stimulation. Generally, when the skin is sensitive, the skin will experience slight stinging, burning, tightness and dryness, and the skin can easily feel itchy, red, swollen, granular or even peeling.
9 major symptoms of skin sensitivity: red rashes Skin sensitivity symptoms 1/ prone to allergic reactions
If you have sensitive skin and your body is prone to allergic reactions due to contact with certain products (such as soaps, cleaning products, perfumes, skin care products, etc.) or external environmental factors (such as sunlight, weather and temperature changes, etc.), it is recommended that It’s best to get tested for allergens and avoid triggers as much as possible.
Skin sensitivity symptoms 2/redness, swelling, and granulation
Most people with sensitive skin will experience repeated blushing, swelling, granulation or even rash. At this time, as long as the source of the allergy is completely eradicated and some simple treatments are performed,
5 incentives to sunbathe every day
#incentives #sunbathe #day
Getting some sun daily offers a variety of health benefits that go beyond simply enjoying pleasant weather. Thus, the question arises: what is the positive impact that vitamin D, obtained directly from sunlight, has on our health?
How is vitamin D made?
What makes vitamin D special is how it is produced. Exposure to the sun, more precisely to UVB rays, initiates a process in the skin that transforms a precursor of vitamin D into the vitamin itself. It is a natural process that our body carries out.
Strengthening bones
Vitamin D plays a vital role in our body, especially when it comes to the health of bones and teeth. It helps regulate calcium and phosphorus, which are essential for keeping our bone structure strong and healthy. A lack of this vitamin can lead to problems such as osteoporosis and rickets, as well as being linked to immune, mental and heart health.
Sun: the best source of vitamin D
Although some foods such as fatty fish, eggs and fortified dairy products contain vitamin D, nothing beats the effectiveness of the sun as a source of this essential vitamin.
Harry and William, the great frost between the brothers: the Duke of Sussex forced to sleep in a hotel in London. And now he immediately returns to the United States-ilgazzettino.it
After the recent announcement of King Charles III’s cancer diagnosis, the tension within the royal family seems to be escalating even further. Prince Harry, who has been estranged from the family since stepping down as a senior royal, was reportedly forced to sleep in a hotel during his recent visit to London.
The Duke of Sussex’s visit to the UK was meant to be a brief and private one, but it seems to have been marred by conflict and discomfort. According to reports, Harry has already left for Los Angeles, just 24 hours after arriving in London. This hasty departure raises questions about the state of his relationship with his family, particularly his brother, Prince William.
Sources close to the royal family have suggested that there is still a great frost between the two brothers, and that their relationship remains strained. The reasons behind this frost are not entirely clear, but it is believed to stem from Harry’s decision to step away from his duties as a senior royal and move to the United States with his wife, Meghan Markle.
The announcement of King Charles III’s cancer diagnosis has also added a new layer of complexity to the situation.
Continued ADHD Drug Shortage Frustrates Many
Continued ADHD Drug Shortage Frustrates Many
Wendy Steele, a 48-year-old from Baltimore, has had difficulty finding pharmacies that stock medications for attention-deficit/hyperactivity disorder (ADHD) prescribed for both her and her 9-year-old son, Colton. Both of them have had to skip, delay, or go without their medications for weeks at a time. Steele believes that the shortage is negatively affecting Colton’s schoolwork, stating, “It’s annoying for me, but it is a really critical medication for my son. And that’s what makes me sad. His education is suffering.”
Personal Stories Highlight the Impact
Patients like Wendy Steele have resorted to calling pharmacies a week before their prescriptions run out to ensure availability. However, ADHD medications are controlled substances and can only be prescribed for 30 days at a time.
ADHD Prevalence and Medication Importance
Dr. Sarah Cheyette, a pediatric neurologist at the Palo Alto Medical Foundation, shares that January was particularly challenging for her patients. Medications like Vyvanse, Ritalin, and Focalin are still difficult to find, leading patients to visit multiple pharmacies and encounter backorders.
High Demand and Manufacturing Challenges
Drugmakers have published estimates for when the medications will be back in stock, but these estimates have repeatedly been pushed back as they struggle to meet demand.
Researchers Create Functional 3D-Printed Brain Tissue for Studying Neurological Disorders
Researchers at the University of Wisconsin-Madison have achieved a groundbreaking feat in the field of neuroscience by creating functional 3D-printed brain tissue that mimics the development and connectivity of real human brain tissue. This remarkable accomplishment has the potential to revolutionize the study of neurological disorders such as Alzheimer’s and Parkinson’s, offering new insights into the communication between brain cells and other parts of the brain.
The team, led by neuroscientist Su-Chun Zhang, believes that their new method can be easily adopted by many labs, as it does not require specialized bio-printing equipment. Moreover, the tissue can be maintained in a healthy state and studied using standard laboratory equipment like microscopes. This accessibility makes it a valuable tool for researchers in various fields, including stem cell biology and the pathogenesis of neurological and psychiatric disorders.
The technique used by the researchers is known as 3D bioprinting, which involves layering materials, cells, and other components to create living structures. While this technology has shown promise in replicating and even replacing tissues, printing functional human brain tissue has proven to be a significant challenge. Previous attempts lacked proper connections between cells and failed to maintain the tissue structure while allowing neurons to mature.
Researchers develop IntelliGenes, software that predicts
The program is presented as a tool that allows you to analyze multigenomic and clinical data efficiently.
Health researchers at Rutgers Health in the US have taken a significant step in disease prediction by developing the revolutionary computer program IntelliGenes. This pioneering software, which combines artificial intelligence (AI) and machine learning, focuses on measuring the relevance of specific genomic biomarkers to predict diseases at the individual level.
In a study published in Bioinformaticsdetails how IntelliGenes It is presented as an accessible tool for a wide range of users. This program allows you to analyze multigenomic and clinical data efficiently, thereby overcoming the barrier of complexity for those who are not experts in the field.
An inclusive approach to genomic research
The study’s lead author and professor at Rutgers’ Institute for Health, Health Policy and Aging (IFH) Research, Zeeshan Ahmed, highlights the lack of AI or machine learning tools to investigate the entire human genome, especially for non-experts. IntelliGenes It has been designed by Ahmed and his team to be accessible to anyone, including students and those without extensive knowledge of bioinformatics techniques or access to high-performance computers.
The Health Risks of Binge-Watching Drama Series: Everything You Need to Know
- February 7, 2024
- No Comments
Taiwanese people love binge-watching drama series. Netflix points out that Taiwanese people are the most successful in the world at this type of series, finishing an average of one drama series every three days! During back-to-back holidays, it’s a good time for many drama fans to binge-watch dramas, but do you know the health risks of binge-watching?
The following days of treatment will resolve the health risks of watching fiction for everyone. I hope everyone can be a little more vigilant while relaxing while watching dramas to avoid harming their health.
Why do you want to watch dramas?
Before we talk about the health risks of binge-watching dramas, I would like to discuss why you want to binge-watch dramas?
Gayani DeSilva, a psychiatrist at the Family Health Center in Laguna, California, said there are two important modes of interaction between the audience and the characters in the play. The first is the audience’s identification with the character, that is, seeing their own shadow in the character.
Netherlands suffers from flu epidemic: They were still lifeless a week later
A flu epidemic has officially broken out in the Netherlands, according to the conclusions of the Nivel research institute, the Erasmus MC and the National Institute for Public Health and the Environment. Last week, GPs at Nivel Sentinel stations diagnosed 70 patients with flu-like symptoms per 100,000 population.
Year ago
GPs then took samples from patients with respiratory disorders and also tested them for respiratory viruses. An increasing amount of influenza virus was found in these samples. Furthermore, the number of patients exceeded 56 for the second consecutive week: the limit above which an influenza epidemic is officially recorded.
According to the RIVM, the last time so many cases of flu were recorded was in January last year.
Laura, 21, from Rijpwetering in South Holland, can unfortunately talk about it. Sniffling and coughing, she s ays into the phone: “I’ve been home sick for a week, but today I went back to work. My presence was very welcome, otherwise it would be chaos. But in reality I’m still lethargic.”
Chills of cold
The assistant has been ill since Christmas. But last Thursday the flu arrived. “I felt very sick to my stomach and on Friday I woke up with chills and a fever.