A recent study conducted by researchers from Canada’s McGill University showed that Nerve injuries Its effects are not limited to the affected area only, but can affect the entire immune system, causing general inflammation in the body.
It was previously known that the immune system plays an essential role in recovery after nerve injuries, which often lead to chronic pain, but new results show that the effect extends more comprehensively, and that the way the immune response differs between males and females.
Difference in immune response between genders
Blood samples were analyzed in mice after nerve injury, and it was found that:
In males: Inflammatory markers rose as expected and remained at high levels.
In females: No increase in inflammatory indicators in the blood was recorded.
However, when blood from infected mice was transferred to healthy mice, they showed increased sensitivity to pain, suggesting a pain transmission factor that differs between the sexes.
Important scientific implications
Researcher Jeffrey Mogil points out that nerve injury is not just a local problem, but can cause long-term changes in the immune system, which may increase the risk of developing several chronic diseases, including anxiety and depression.
The results also showed that the substance responsible for pain in females works through a completely different biological pathway, which scientists need to understand more deeply in the future.
The importance of research
This study provides new insights into:
The relationship between the nervous system and the immune system
Biological sex differences in inflammatory response
The possibility of developing gender-specific treatments to improve recovery from nerve injuries
