Likely The NPCs in this Village Sim Game Must Be Real!
Here’s a synopsis from MangaDex:
An unknown parcel arrives to Yoshio, a 30-year old NEET. The content
is a game disk titled “The Village of Fate”, a beautiful CG game with
real-life images.All of the villagers in the game are high-performing AIs, who behave
remarkably close to human beings. In the game Yoshio takes the role as
the god of destiny and is in a position to guide the villagers. But
his only options in the game are to give a message, a prophecy, once
every day. The villagers will follow the instruction, and their
gratitude transforms to the power of miracles, which the god of
destiny can use.Yoshio is worshiped as God but in reality he lives like a shut-in.
Thanks to villagers he will again learn the joy of life and thanks to
him the villagers will be saved.
While it claims the villagers are AI, the protagonist figures out that they’re real not long into the story.
