A female Alzheimer’s disease in a French recuperation village. (AFP archive photo)
Li Huifen/Reviewed Manuscript Edit
[Compiled by Guan Shuping/Comprehensive Report]A study from King’s College London, UK recommends that women should ensure that they consume enough Omega fatty acids in their diet, because the study found that women with Alzheimer’s disease have abnormally low unsaturated fat values, including Omega fatty acids, are suspected to be causal to Alzheimer’s disease.
The British “Guardian” reported on the 20th that the research team analyzed blood samples from patients with Alzheimer’s disease and healthy people and found that the unsaturated fat value in the blood of female patients is as low as 20% lower than that of healthy women, while male patients did not see this phenomenon, which means that there are gender differences in the occurrence of Alzheimer’s disease and its physiological impact on the patient.
“The difference between the genders is the most surprising and surprising finding,” said senior author Cristina Legido-Quigley, an associate professor at the Institute of Pharmacy at King’s College London. “There are signs that this type of lipid is a causal relationship with Alzheimer’s and Dementia on the 20th. “There are signs that this type of lipid is likely to have a causal relationship with Alzheimer’s disease, but we still need clinical trials to confirm this.”
The rate of Alzheimer’s disease in women is about twice that in men. The new study analyzed blood fat mass in 306 patients with Alzheimer’s disease, 165 people with mild cognitive dysfunction, and 370 controls with cognitively healthy functions. Fats are divided into saturated and unsaturated fats. The former is considered unhealthy and the latter is widely considered to be healthy fats.
The analysis found that women with Alzheimer’s disease have higher saturated fat and lower unsaturated fat. Reshido Quigley said that if this is due to liver or metabolic changes, it may cause less Omega fatty acids to enter the brain, “and these fats can provide brain nutrients.”
Diets rich in Omega‑3 fatty acids, such as the Mediterranean type, have long been believed to be related to the health of tissues such as the heart and brain. A 2022 study pointed out that middle-aged people have a higher content of Omega-3 fatty acids and have better cognitive function; however, many trials have also shown that giving older people with Omega‑3 supplementation has not been determined to improve their cognitive function or improve the mental ability of confirmed patients.
Reshido Quigley hopes to design clinical trials for women with low unsaturated fatty acid values to verify whether supplementing this type of substance can delay the disease. Research points out that the reduction in this type of fat may begin to appear in the 50s. At the same time, she also advised that women should ensure they consume enough Omega fatty acids in their diet.
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