New research indicates that incorporating regular physical activity into the recovery plan for colon cancer patients can significantly decrease the likelihood of the cancer returning. The international study, known as the CO21 Challenge trial, highlights the potential of exercise to not only improve mood, reduce fatigue, and increase strength, but also to prevent recurrence.

Colon cancer,often referred to as bowel or colorectal cancer,develops in the colon,which is part of the large intestine. According to estimates, tens of thousands are diagnosed annually in the UK alone.

The CO21 Challenge trial, conducted by researchers in Northern Ireland and Canada, involved nearly 900 individuals with colon cancer from six countries, including the UK. All participants had undergone surgery and chemotherapy and were physically capable of exercising but were not meeting recommended activity levels.

Approximately half of the participants were assigned a three-year personalized exercise program that included activities like brisk walking, circuit training, cycling, and swimming. This program featured initial in-person coaching sessions and regular consultations with a physical activity consultant. The remaining participants received materials promoting exercise and nutrition.

The study revealed that after five years, the group with the tailored exercise plan experienced a 28% reduction in the risk of death, relapse, or advancement of a new cancer. After eight years, this group saw a 37% lower risk of death.

expert Insights on Exercise and Cancer Recovery

“Our study gives clear, encouraging evidence that physical activity can reduce the risk of cancer returning for some people with colon cancer.”

Professor Vicky Coyle, clinical professor at Queen’s University Belfast and UK lead researcher for the trial, emphasized the importance of tailoring exercise to individual needs. “During the trial,we supported people to reach their weekly exercise target in a way that worked for them,” she said. “This could be a brisk walk for around 40 minutes every day, but some patients were also doing circuit classes, cycling, swimming, and many other activities.”

Dr. Joe Henson, associate professor in lifestyle medicine at the University of Leicester, observed firsthand the positive effects of exercise on patients. “Leading the exercise sessions in Leicester,I saw first-hand that this reduced fatigue,lifted people’s mood,and boosted their physical strength,” he noted,adding that further research could uncover the biological mechanisms behind these benefits.

The study’s findings, published in the New England Journal of Medicine and presented at the American Society of Clinical oncology (ASCO), have the potential to reshape clinical practices, according to experts.

Caroline Geraghty, senior specialist details nurse, highlighted the broader benefits of physical activity. “Being active has many benefits, and this study shows that exercise doesn’t only improve well-being – it can also boost people’s chances of surviving colon cancer,” she stated. She also advocated for access to tailored support for cancer survivors to improve their quality of life.

Professor Peter Johnson,NHS national clinical director for cancer,echoed these sentiments,noting the growing evidence supporting the role of physical activity in cancer recovery. He stated that cancer alliances are exploring ways to encourage and support patients in engaging in physical activity throughout their cancer journey.