Jason Gardosi and colleagues’ trial provides important information regarding the choice of delivery for a fetus with an ultrasound-predicted weight exceeding the 90th percentile.1 The appendix of the Article provides a breakdown of the relative effect estimates for babies with a predicted weight above or below the 95th percentile within the top decile range. However, these estimates are very imprecise (despite the study’s large size) and are expressed in relative, not absolute, risk terms. In some trials, such as those on the risks and benefits of anti-hypertensive treatment, it is possible to titrate effectiveness against baseline risk with reasonable precision.
Big Baby Trial: Induction of Labour for LGA Fetuses – Rethinking Practice
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