Addressing Critical Health Challenges Through Innovative Research

The Faculty of Human Medicine at the University of Piura (UDEP) is set to spearhead six new research projects this year,focusing on key areas such as medical education,oncology,antimicrobial resistance,and chronic cervical pain. These studies, driven by the faculty’s research-oriented educators, aim to produce robust scientific evidence while actively involving students through research assistantships.

Scientific research forms a cornerstone of the Faculty’s mission.By investigating diverse health domains, UDEP seeks to generate knowledge that directly addresses pressing health issues within Peru and beyond. This commitment underscores the university’s dedication to improving healthcare outcomes through evidence-based solutions.

Enhancing Medical Education: A Focus on Assessment and Performance

Two distinct studies will delve into the Faculty’s experiences with the annual examination, a progress assessment tool implemented by the Professional School of Human Medicine since 2017, and the National Medicine Exam (ENAM). Professor Franco Romaní will lead both investigations, with the overarching goal of elevating the quality of medical training.

One project will meticulously analyze the evolution of student performance in the annual exam. This summative evaluation serves as a crucial mechanism for monitoring learning progression throughout the medical program. The second project will explore the predictive relationship between students’ weighted grade point average and their performance on the ENAM, a high-stakes exam administered at the culmination of their studies. Understanding this correlation can provide valuable insights into academic preparedness and areas for improvement.

These studies are crucial for understanding the effectiveness of our educational programs and identifying areas where we can better support our students’ success.

Professor Franco Romaní, University of Piura

Oncology Research: Exploring Novel Therapeutic Strategies

Two studies will explore innovative strategies to improve the treatment of various types of tumors. These projects reflect a growing emphasis on precision medicine and targeted therapies in oncology.

Professor Juan Enrique Faya will lead a project evaluating the stability of Nisina, a bacterial peptide exhibiting potential anti-tumor effects in hepatocarcinoma (liver cancer). Simultaneously, another study will analyze the use of siRNAs (small interfering RNAs) to inhibit the Kinase Alk in non-small cell lung cancer. This therapeutic approach holds promise for delivering more effective and less toxic treatments, aligning with the principles of precision medicine. Lung cancer, for example, remains a leading cause of cancer-related deaths worldwide, highlighting the urgent need for innovative therapies.

Combating Antimicrobial Resistance: Understanding Resistance Mechanisms

Antimicrobial resistance (AMR) poses a significant and escalating threat to global public health. The World Health Association (WHO) considers AMR one of the top 10 global public health threats facing humanity. As available treatments become less effective, managing serious infections becomes increasingly complex and costly.

Dr. Edgar Gonzales Escalante will spearhead a study focused on the biochemical and structural characterization of AAC(6′)-Ian and AAC(3)-IIa enzymes. These enzymes are responsible for modifying aminoglycosides,leading to resistance against these antibiotics. By gaining a deeper understanding of these resistance mechanisms, researchers can lay the groundwork for developing new drugs and more effective therapeutic strategies to combat AMR.

Understanding the intricate mechanisms of antimicrobial resistance is paramount to developing effective countermeasures and safeguarding public health.

Dr. Edgar Gonzales escalante,University of Piura

Investigating Chronic Cervical Pain: An epidemiological Approach

Professor Tomás Nakazato will direct a two-year population monitoring study to assess the impact of social restrictions implemented during the COVID-19 pandemic on the prevalence of chronic cervical pain. The research will also analyze the correlation between the use of electronic devices and the occurrence of this type of pain.

This epidemiological research aims to provide valuable insights into the potential long-term health consequences of pandemic-related lifestyle changes and the increasing reliance on digital devices. The findings could inform public health recommendations and interventions aimed at preventing and managing chronic cervical pain.

Ethical Oversight

All research projects have received approval from the Ethics Committee on research at the University of Piura,ensuring adherence to the highest ethical standards in research conduct.