A key to treating pancreatic cancer?

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Cannabis compounds fight cancer cells

Cannabis appears to be a new effective cure for pancreatic cancer. In the first trials, treatment with specific compounds derived from cannabis resulted in the complete disappearance of tumors.

Research from the internationally recognized Harvard University showed that cannabis appears to be very effective in the treatment of pancreatic cancer. The results of the study were published in the English-language journal "Frontiers in Oncology".

A selection of medicinal cannabis products.
Will we treat various serious diseases with cannabis in the near future? (Image: Elroi / fotolia.com)

Pancreatic cancer usually ends in death

In the study, treatment of mice with pancreatic cancer based on cannabis-derived compounds caused the tumors to disappear completely. In 70 percent of the mice with pancreatic cancer, the treatment actually killed all tumors, the researchers report. The chance of surviving pancreatic cancer is unfortunately very low. Pancreatic cancer usually causes 93 percent of those affected to die within just five years.

Flavonide for the treatment of cancer?

Pancreatic cancer is one of the most difficult forms of cancer to treat. However, researchers have discovered that so-called flavonoids, compounds present in most plants, make effective treatment of the disease possible. Flavonoids are neither a cannaboid nor a psychoactive component. They differ from the more frequently consumed forms of cannabis, such as CBD oil or marijuana-fortified foods. There are more than 6000 different variations of flavonoids. The Harvard University research group recognized the great potential of one of these substances, which was identified in cannabis and used to make a substance called FBL-03G. This can reduce unpleasant side effects of standard cancer therapies such as chemotherapy and radiation.

Cannabis plants produce different amounts of active ingredients

The results were surprising and additional measurements were taken to verify their reliability, the researchers report. It was confirmed that cannabis can stop the spread of cancer cells and even reduce the cancer of a cancer patient by half. Studies on cannabis and cancer have shown that cannabis partly had an impact on cancer treatment and partly not. Many of the differences in these studies are due to the wide variation in the composition of certain cannabis or cannabis plants, the researchers explain. For example, every cannabis plant produces completely different amounts of active ingredients.

The results were partly surprising

Cannabis was previously expected to cause some inhibition of tumor growth, but researchers were quite surprised that the treatment also inhibited the spread of the tumor to other parts of the body. It is unclear whether the cancer will return, but for the time being most mice were free of cancer, the research group reports. (As)

sources:

  • Michele Moreau, Udoka Ibeh, Kaylie Decosmo, Noella Bih, Sayeda Yasmin-Karim et al .: Flavonoid derivatives of cannabis show therapeutic potential in preclinical models of metastatic pancreatic cancer, in Frontiers in Oncology (query: 23.08.2019), Frontiers in Oncology

. (TagsToTranslate) cancer (t) pancreatic cancer (t) Cannabis (t) tumor (t) FBL 03G

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