Home Health a blood test for diagnosis soon?

a blood test for diagnosis soon?

By analyzing the blood of patients, American researchers have defined a feature of "molecular signature" for fibromyalgia. These results make it possible to consider the development of a simple and rapid test for the diagnosis of this disease.

the fibromyalgia is a chronic disease that is characterized by pain diffuse and persistent, often accompanied by other examples of symptoms
The symptoms can affect various organs:

muscle pain, joint pain, headache, digestive problems, disorders of … "data-image =" https://fr.cdn.v5.futura-sciences.com/buildsv6/images/midioriginal/e/8/ 8 / e882bacd5b_96032_symptome- woman-mal-head.jpg "data-url =" / health / definitions / medecine-symptom-834 / "data-more =" Read more ">symptoms : intense tiredness, sleep disorders, problems with concentration and memory, anxiety, headache… In Europe, according to the health insurance websiteabout 2% of the population would be concerned.

Fibromyalgia is often incorrectly diagnosed, so patient fatigue and pain are not always treated well. To diagnose the disease, the doctor relies on the symptoms described by the patient, including pain. In general, exercise is advised to patients. of the painkillersas opioidscan be prescribed, sometimes even different categories. "data-image =" https://en.cdn.v5.futura-sciences.com/buildsv6/images/midioriginal/2/0/6/206198d4f0_50034561_depression- man-phovoir.jpg "data-url =" / health / definitions / medicine-antidepressant-3685 / "data-more =" Read more ">antidepressants. But some doctors doubt the reality of this disease.

For now there is no blood test for fibromyalgia. The existence of a test would allow better recognition of this disease and more appropriate treatment. That's why researchers at Ohio State University wanted to find fibromyalgia biomarkers that differentiate this disease from others pathologies family members. For this they studied the blood of 50 patients with fibromyalgia, 29 with rheumatoid arthritis, 19 withosteoarthritis and 23 from lupus.

A characteristic molecular characteristic of the disease

Patients' blood was analyzed using a technique called vibrational spectroscopy, which measures the level ofenergy The so-called simple covalent binding … "data-image =" https://www.cdn.v5.futura-sciences.com/buildsv6/images/midioriginal/d/0/e/d0e3dc7e1e_76472_molecule.jpg "data-url = "/ sciences / definitions / chemistry-molecule-783 /" data-more = "Read more">molecules. This allowed the researchers to define a characteristic profile of patients with fibromyalgia, which was different from patients with similar pathology, as explained Kevin Hackshaw, rheumatologist and lead author of this study published in the journal Journal of Biological Chemistry : "We have found reproducible and clear metabolic patterns in the blood of dozens of patients with fibromyalgia."

This work could identify specific molecules of the disease and propose a blood test. For Luis Rodriguez-Saona, who also participated in this study, and who expresses himself in one statement from Ohio State University: "These initial results are remarkable. If we can help speed it up diagnosis in these patients their treatment will be better and they will probably have better prospects. There is nothing worse than being in a gray area where you don't know what illness you have. " In addition, the test can give an idea of ​​the severity of the disease.

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Fibromyalgia often worsens with opioids and certainly does not improve

According to Kevin Hackshaw, the molecular signature of the disease can also pave the way for new ones treatments focused, more suitable than painkillers opioids, which he considers ineffective in the case of fibromyalgia: "In chronic pain clinics, about 40% of opioid patients meet the diagnostic criteria for fibromyalgia. Fibromyalgia often worsens with opioids and certainly does not improve."

The next step for researchers will be to get one clinical trial to evaluate this still experimental blood test.

What to remember

  • Fibromyalgia is a chronic disease that has been incorrectly diagnosed.
  • It causes persistent pain and intense fatigue.
  • American researchers have found a molecular characteristic that is characteristic of the disease by analyzing the blood of 50 patients.
  • This discovery paves the way for the development of a quick and easy blood test.

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